Article

March 13, 2026

time

-min

read

Recovery

Can Vagus Nerve Stimulation Help People Get More Exercise?

What if recovery, not effort, is the real bottleneck in your fitness routine? New research suggests vagus nerve stimulation may reduce fatigue, ease soreness, and help your body bounce back faster after workouts.

Two older adults jogging together along a tree-lined path on a sunny day.

In a nutshell

  • Recovery drives long-term fitness. Consistency matters more than single-session performance and influences recovery between workouts.
  • Chronic stress can slow recovery. A constantly active stress response may increase inflammation and fatigue and delay tissue repair.
  • The vagus nerve regulates recovery. As a key part of the parasympathetic nervous system, it helps shift the body into a rest-and-repair state.
  • Vagus nerve stimulation may improve post-workout recovery. Studies show it can reduce muscle pain, fatigue, and post-exercise sympathetic overactivity.

If you're trying to build a consistent exercise habit, you already know the hardest part is showing up again and again, when your legs are still heavy from the last session, your shoulders ache when you lift your arms, and every warm-up rep feels like a negotiation with your body.

But what if you could recover just a little faster?

Recovery is central to a healthy exercise routine, but it is often limited by physiological, nutritional, and lifestyle factors. One of the most important is the stress-inflammation cycle.

After a tough workout, your body launches an acute stress-inflammation response. Microscopic damage occurs in your muscle fibers, and your immune system moves in to clean up the damaged tissue. This triggers a highly regulated, self-limiting process that ultimately leads to muscle regeneration. In other words, the soreness you feel the next day is part of the repair process that makes your muscles stronger.

But this system only works well if the stress response switches off afterward.

If the stress-inflammation cycle stays active, because of poor sleep, chronic stress, overtraining, or inadequate nutrition, your body struggles to shift into its rest-and-recovery mode. Instead of calming down after exercise, your stress response keeps running in the background.

Your stress hormones become chronically dysregulated, and cortisol levels remain elevated long after the workout ends. Over time, glucocorticoid receptor resistance can develop, meaning cortisol no longer triggers the anti-inflammatory response it is supposed to produce.

The result is familiar to many people who exercise regularly: soreness that lingers for days, workouts that feel harder than they should, and fatigue that builds week after week.

Inflammation rises, tissue repair slows, energy drops, and performance begins to stall.

Researchers have been studying whether vagus nerve stimulation can interrupt this cycle to reduce post-exercise fatigue, accelerating recovery, and even making it easier to return for the next workout. The findings are nuanced, but more promising than you might expect.

Vagus nerve stimulation crash course

The vagus nerve is the longest cranial nerve in the body, running from the brainstem down through the heart, lungs, and digestive tract. It's a central highway of the parasympathetic nervous system, the rest-and-digest branch that counterbalances the stress response.

Vagus nerve stimulation (VNS) involves activating this nerve either through implanted devices or, increasingly, through non-invasive methods like transcutaneous auricular VNS (taVNS), which delivers gentle electrical pulses to the outer ear. No surgery required.

Does VNS actually improve performance?

Let's get the most common question out of the way first: no, VNS won't make you faster or stronger in a single session.

In a study of 90 healthy young adults performing a 30-minute maximum-effort cycling test, taVNS did not increase total distance cycled. Raw athletic output depends more on training, motivation, and conditioning than on nerve stimulation.

But performance during a workout is only part of the equation and arguably not the most important part for long-term fitness.

Long-term fitness is built through consistency, and consistency depends on how well you recover between workouts.

Here's where VNS research gets genuinely interesting.

Reduced muscle pain and fatigue

In a study where participants received bilateral VNS after exercise, they reported significantly less muscle pain and lower perceived fatigue compared to control groups.

If post-workout soreness is what keeps you off the treadmill for days at a time, this has real practical value.

Faster nervous system recovery

During exercise, your sympathetic nervous system (fight-or-flight) dominates, and rightfully so. The problem is that staying in that heightened state after your workout delays recovery and disrupts sleep.

VNS has been shown to:

Crucially, this shift happens without dangerous cardiovascular side effects.

Lower lactic acid levels

Participants in the pain and fatigue study who received bilateral VNS after exercise showed significantly lower blood lactic acid levels.

Lactic acid is a key driver of that heavy, burning sensation in your muscles during and after intense effort. Lower levels post-workout suggest more efficient anaerobic metabolism and improved parasympathetic recovery, which may translate into less next-day sluggishness and stiffness.

Can VNS help you want to exercise?

This is perhaps the most intriguing area of current research.

Emerging evidence suggests VNS may influence motivation, reward processing, and mood. In some studies, non-invasive VNS boosted motivation to work for rewards and improved mood recovery after exertion, particularly in people who started with lower baseline mood or energy.

VNS won't override your reluctance to exercise entirely, but it may reduce the psychological friction that stops you from lacing up your shoes some days.

Recovery optimizer, not performance enhancer

Vagus nerve stimulation won’t make you stronger, faster, or more flexible. But, by speeding recovery, reducing pain, and boosting motivation, VNS may make the next workout more likely.

In the long game of fitness, recovery is what determines sustainability.

Did you know?

Exercise itself stimulates the vagus nerve. VNS doesn't replace physical activity. It supports it.

Up next

View All
Portrait of Dr. Lou Atkinson, Ph.D., yōjō Health guest author, against a pastel gradient background.
Stress

Article

August 14, 2026

time

-min

read

How Do You Know If Your Nervous System Is Dysregulated?

"I just feel a bit off, not myself, but I don't really know why." Here’s why.

As a wellbeing coach and health psychology specialist, I've worked with hundreds of clients — executives running global teams, athletes preparing for competition, busy working parents spinning a dozen plates — and one of the most common things I hear, in slightly different words each time, is: "I just feel a bit off, not myself, but I don't really know why."

What strikes me is how rarely people connect that feeling to their nervous system.

It's not their fault. Nervous system regulation isn't something we're taught about in school, and the symptoms often don't feel serious enough to bring to a healthcare professional.

So when something feels off, most people don't know where to look for answers. And they end up tolerating a low-grade version of themselves for months, sometimes years, before joining the dots.

So before we get into this further, let’s do a simple check-in to see if your nervous system might be a little out of sorts.

A few questions to ask yourself

Sit with these for a moment. There's no scoring system, and this isn’t a diagnosis. Just be really honest about whether any of these describe you right now, and if there’s a pattern across more than one area.

  1. Do you find it hard to fall asleep even when you're exhausted? Do you wake at 2 or 3 am with a busy mind? Or, do you get a full night’s sleep yet wake unrested?
  2. Do you feel "tired but wired", too depleted to do much and too revved up to rest? Do you crash in the afternoons, then get a second wind late at night?
  3. Is your concentration patchier than it used to be? Are you losing words mid-sentence, walking into rooms and forgetting why, or finding tasks that used to be easy harder?
  4. Are you more reactive than usual — tearful, snappy, anxious — over things that wouldn't normally land that hard? Or the opposite: flat, numb, a little disconnected from yourself and the people around you?
  5. Is your jaw tight? Shoulders up by your ears? Heart occasionally racing for no clear reason? Has your digestion become unpredictable? Do bloating, reflux, irregular bowels, sensitivities seem to be multiplying?
  6. When something stressful happens, how long does it take you to genuinely come back down? Hours? Days? Or does it feel like you never quite return to baseline at all?

If you're nodding along to several of these — particularly across more than one category — it's worth taking seriously. This is what a dysregulated nervous system tends to look like in real life. Not dramatic. Not always alarming. Just a steady accumulation of small signals.

Why this happens — even when you're coping

Here's the part that often lands hardest with my clients: you can be coping and be dysregulated at the same time. In fact, that's the most common presentation I see.

You're still showing up, still hitting deadlines, still being a good parent, a reliable friend, a strong performer. From the outside — and often from the inside too — it looks like things are working. And they are, but your body is keeping score. And it's beginning to show you, in quiet ways, that the system needs some help.

To understand why, it helps to know a little about how your autonomic nervous system works.

Your autonomic nervous system has two main branches, the sympathetic (fight-or-flight) and the parasympathetic (rest-and-digest). A balanced system switches fluidly between the two throughout the day. You ramp up for a meeting, then come back down. You handle a stressful conversation, then return to baseline. That movement between states is what we mean by regulation.

Dysregulation isn't about being stressed. It's about losing the ability to come back down. When the body lives in a state of low-grade activation for long enough — from demanding work, caring responsibilities, illness, unresolved emotional load, or simply years of pushing through — the system stops returning to baseline between stressors.

Your sleep gets lighter. Your digestion gets touchier. Your mood gets thinner. Your thinking gets foggier. None of it is dramatic in isolation. All of it points to the same underlying issue.

The symptoms above, while seemingly random and tied to character flaws, are just your physiology responding to you running hot for too long without a proper reset.

Where to go from here

The first piece of work is recognition, which is what this article has really been about. And it is what asking yourself those questions at the top will help ignite. And if they have helped you identify something worth addressing, there is good news.

Your nervous system can relearn any flexibility it may have lost.

Quitting your job, ditching your caring responsibilities, or running away to a tropical island won’t help you rebalance your nervous system long-term. Teaching your system that it's safe to come down will. Consistently engaging in small daily rituals that activate your rest-and-digest response helps your body to learn how to switch back into this mode more easily and fast-track you back to feeling more like yourself.

Dr. André Boezaart, Chief Medical Officer, guest author portrait.
VNS

Article

August 7, 2026

time

-min

read

Dr. André Boezaart’s Perspectives on nVNS

yōjō Chief Medical Officer, André Boezaart, reflects on stress, the senses, and the vagus nerve.

By André P. Boezaart, MD, PhD, FASRA

It helps to think of the human nervous system as four connected parts, each with its own job.

The central nervous system (CNS) is the brain and spinal cord. It is the command center. It handles thoughts, feelings, and decisions.

The autonomic nervous system (ANS) runs the jobs you never think about but can't live without: your heartbeat, your breathing, digestion, and blood flow.

The somatic nervous system (SNS) controls the movements you choose to make and facilitates your senses. It is your link to the outside world.

The enteric or "gut" nervous system (GUT) lives in your digestive tract. It has more nerve cells than your spinal cord, and it acts like a mind of its own, talking to the brain all day through nerve and chemical signals.

Together, these four systems work like a piece of music. Each part matters. Harmony is the goal. When one section plays too loudly, the whole piece falls out of tune.

When the stress system gets stuck

Inside the autonomic nervous system are two branches that keep each other in check.

The sympathetic system is the accelerator (fight-or-flight). The parasympathetic system is the brake (rest-and-digest).

In modern life, the accelerator often gets stuck. Alerts, deadlines, and worry keep the sympathetic system running hard, all the time.

What was meant for short bursts of alertness becomes prolonged hypervigilance. What was meant to be a useful alarm turns into slow harm.

A gland called the adrenal medulla releases catecholamines (stress hormones like adrenaline) and doesn’t stop. And another system, the hypothalamic–pituitary–adrenal (HPA) axis, releases cortisol, and doesn’t stop.

The immune system slips into a low, simmering, inflamed state. Inflammatory signals called cytokines rise, blood vessel linings work less well, and the gut wall becomes leakier and weaker.

The nervous and immune systems, which are meant to be partners, start working against each other.

Calming the body through the senses

You wouldn’t think it, but your senses play a role in spreading calm throughout your nervous system. Each of the five senses offers a direct path to the parasympathetic system. These paths evolved to tell the body one thing: you are safe.

Sight. When your eyes rest on something wide and open, like mountains or the ocean, the visual part of the brain sends calming signals inwards. This lowers activity in the amygdala, the brain's alarm center. A soft, wide gaze actually slows your heart.

Hearing. Gentle, patterned sounds calm us. Think of a mother's sing-song voice to a baby, a soft hum, ocean waves, or soothing music. These sounds work the tiny muscles in the middle ear and activate the vagus nerve. Your body tunes toward connection instead of defense.

Smell. Scent has a direct line to the brain's emotion centers. Aromas like lavender, bergamot, and frankincense lower stress activity and lift vagal tone (the strength of the calming vagus nerve).

Taste. Eating mindfully wakes up taste nerves that run along cranial nerves VII, IX, and X. This releases feel-good chemicals like dopamine and endorphins and gets digestion moving, which is part of the vagus nerve's territory.

Touch. Massage, firm pressure, and gentle skin contact switch on special nerve fibers called C-tactile afferents. These signal safety and belonging. They raise oxytocin (a bonding hormone) and boost the calming system.

Put together, these signals tell the body you are safe and free to heal.

The vagus nerve: the body's anti-inflammation highway

At the center of all this calming is the vagus nerve, the tenth cranial nerve. It is a two-way highway linking the brain, the organs, and the immune system.

About 80% of its fibers are afferent, meaning they carry information up to the brain. They send sensory signals from the organs and body, including from parts of the outer ear called the cymba and cavum conchae, back to the brainstem.

Its efferent fibers carry signals the other way, down from the brain. They switch on the cholinergic anti-inflammatory reflex.

Here's how that works: the vagus nerve releases a chemical called acetylcholine. It attaches to receptors on immune cells called macrophages. This lowers inflammatory signaling.

This link between the nervous and immune system is what allows thought, emotion, and inflammation to "talk" to each other in real time.

Bundling the senses at the ear

When we stimulate the part of the vagus nerve in the outer ear, in the cymba and cavum conchae, we tap straight into those calming afferent (sensory) pathways.

Transcutaneous auricular vagus nerve stimulation (taVNS) sends gentle electrical pulses to the very same circuits that music, touch, scent, and beauty stir up on their own.

It's as if all five senses were bundled into a single clear signal, all arriving together at a hub in the brainstem called the nucleus tractus solitarius.

Then, using the vagus nerve, the brain sends calming signals back down into the body. It steadies the heart, settles the gut, and quiets inflammation through that same acetylcholine pathway.

taVNS does not replace the senses. It amplifies their message. It reminds the nervous system what safety feels like.

Closing thought

At its heart, the path from stress to healing is a shift from sympathetic noise to parasympathetic calm.

Beautiful views, gentle sounds, soothing scents, delicious meals shared with loved ones, and a caring touch all send the same message the vagus nerve carries in every heartbeat: Be still.

A man lying awake in bed, looking pensively toward the camera.
Stress

Article

July 10, 2026

time

-min

read

Why Am I Wired but Tired — Even After Sleep?

While it feels like a sleep thing, feeling wired but tired is more a sign of nervous system dysregulation.

Key Takeaways

  • Chronic stress keeps your body's alert system turned on — even after the threat is gone.
  • At the same time, stress causes low-grade inflammation. This makes your brain trigger fatigue, low mood, and withdrawal.
  • These two forces pull in opposite directions: one demands alertness, the other demands rest.
  • Sleep can't fix this because nervous system dysregulation is the problem.
  • The fix is achieved through improved vagal tone.

You slept. Properly. Not just an hour or two, but a full night. You canceled the meeting that was draining you, and your bloodwork came back fine, yet your body feels like it's bracing for something.

There is a reason you're feeling “wired but tired”, and it is why almost everything you try to fix the problem fails.

Let’s look at the wired part, then the tired part, before moving on to sleep.

Wired

Over time, chronic stress not only keeps the stress response going, but it also damages the mechanisms that are supposed to end it.

The stress response is managed by a system in the brain called the HPA axis.

Under normal stress, this system releases cortisol — a stress hormone — and then switches off. Under chronic stress, the off switch stops working.

Cortisol levels stay elevated. The nervous system keeps producing alerting chemicals, keeping the brain on edge even when there's nothing to be on edge about.

The nervous system can't easily tell the difference between an active threat and a habitual one. After enough time on high alert, it starts to treat that state as normal. The alarm doesn't turn off because the system has decided quietly and incorrectly that this is just how things are now.

This is the wired part.

Tired

There's a second consequence of sustained stress: low-grade inflammation.

Your fight-or-flight response evolved to prepare the body for injury. So stress primes an inflammatory response just in case you get hurt. Under chronic stress, that response never fully switches off. Inflammatory signaling proteins called cytokines stay elevated in your blood.

These pro-inflammatory cytokines talk directly to your brain, and their message is simple: there is an emergency, and we need to save energy for it. The brain responds with a set of changes that we all associate with being sick: deep fatigue, low mood, reduced motivation, social withdrawal, and difficulty thinking clearly.

What these days is often taken for weakness is merely an energy-saving strategy. Your body is doing exactly what it is built to do. It has just incorrectly decided that the threat is still active.

This is the tired part.

Why sleep doesn't fix it

Sleep can’t resolve this problem because sleep happens on top of this high-alert state.

In a healthy system, cortisol is highest in the morning and lowest at night. This helps regulate when you feel awake and when you feel sleepy. Under chronic stress, this rhythm gets disrupted. Your nervous system stays activated into the evening, making it harder to fall asleep and less likely for sleep to feel restorative.

Getting out of this loop requires nudging your body out of stress mode and into recovery mode.

And your vagus nerve is key here. It helps manage inflammation and is the pathway your body uses to switch from stress to rest.

What the target actually is

The underlying issue is an imbalance in the autonomic nervous system. The alert system is stuck and becoming sensitive to threat signals while the recovery system has lost its grip. The fix, then, has to address that directly.

The target is vagal tone.

Not a one-off reset, but a consistent practice that gradually shifts the nervous system back toward balance.

Evidence suggests that regular activation of the recovery system — through breathwork, vagus nerve stimulation, and structured recovery practices — can build resilience against chronic stress. It can reduce the inflammatory signals driving fatigue and help the nervous system relearn what calm feels like.

Wired but tired has a specific mechanism and specific target. A binge of sleep will help in many other ways, but for this dysregulation, small, repeated inputs matter more than dramatic resets.